a Faculty of Chemistry, University of Warsaw, Pasteura 1, 02093 Warsaw, Poland
b Faculty of Chemistry, Warsaw University of Technology, Noakowskiego-3, 00664 Warsaw, Poland
c Institute of Physical Chemistry, Polish Academy of Science, Kasprzaka 44/52, 01224 Warsaw, Poland
d Institute of Organic Chemistry, Polish Academy of Science, Kasprzaka 44/52, 01224 Warsaw, Poland
First published online 5 Jan 2016.
Front Cover, Very Important Paper.
Zinc tert-butyl peroxide-based catalysts for the asymmetric epoxidation of enones using tert-butyl hydroperoxide as an oxidant have been developed. A comparative study of chiral monoanioninc N,N′-bidentate ligands, C2-symmetric bisoxazolinates and C1-symmetric enaminooxazolinates, revealed excellent performance of C1-symmetric auxiliary ligands on catalytic asymmetric epoxidation of enones (up to 96% yield, 91% ee).